About The Samjalpa
Editorial
Quote of the issue
Article of the issue
Debate of the issue
Plant of the issue

About the Samjalpa
It is a bi-monthly newsletter from Hitayu available free to those who are subscribed to it or who visit our site. It is an informative and interactive platform pertaining to health, herb and humans.

Editorial - A tiny commencement
As Hitayu takes its first step towards facilitating better global health through dissemination of correct information & knowledge and rendering better services - we can wel percieve the herculean task ahead. We humbly acknowledge our tiny stature and lack of perfection on our part to deliver all the goods. But we are also confident that this small beginning in a right and much needed direction will pave the way for
a better informed world.

A Bird's eye view of the global health scenario reveals the shift towards natural from synthetic owing to apparent failure on the part of the latter to solve the health problems confronting the contemporary world. Contingent upon its inherent strength and versatile efficacy Ayuveda has steadily gained popularity and acceptance worldwide. But, unfortunately the world population,by and large, are fed with incomplete, distorted and oppotunistic information regarding Ayurveda - partly due to the subtle intricacies of the subject, partlydue to unfamiliarity of the western world to the principles of Ayurveda and more due to vested commercial interests.

The other face of the coin shows a bullish growth in global herbal market.But the real scene here is also not much greener because the market is highly volatile, typically secretive and opportunistic devoid of any channel of communicatoion.against these developments in backdrop, Hitayu team felt a correct and adequate information portal has to be put in place to help all the stake holders of the industry.Considering the vastness of the subject, magnitude of the problem, it is imperative that there will be difference in opinion. But we believe this difference in oppinion should not stop here rather a meaningful debate should be initiated to to find a logical solution to the issue concerned. The concept behind this newsletter is primarily to provide such a desk for exploring relevant importance and interpretation of an ancient principles in contemporary context.


Quote of the issue
"Yavanto ho loke murtimanto bhavavisheshastavantah purushe;
                                                                         yavantah purushe tavanto loke.

All that occur in nature are also found in humans and all that is present in us are also accoste in nature.This verse of Chraka is a typical example of Indian way of expressing the principles of universe in the most generalized format from which
all the realted facts can be interpreted. this verse says humans like universe is a manifestation of five basic elements in a particular combination and configuration. it also reflects that all visible and invisible attributes found in our nature is also found in our bodies in a miniature form. for example: fire is present in us as pitta and performs the same work of disintegarting in body. The message behind this verse is the close similarity of us and universe and thus the harmony between macro- and micro-cosmos is crucial for us to stay healthy.


 

Placement of a Herb in Global Market

Dr. Sudipt Rath
&
Dr. Purvi Shanghvi
info@hitayu.com
 

Introduction

Our world is witnessing a steady shift to herbals from chemical in all spheres of life,
be it health care, be it food or personal care or cosmetics. Consequent of this development the global herbal market is growing at healthy rate of 7% per annum. It has opened up new avenues for economic benefits for countries rich in bio resources. Many countries like China, Thailand, United States and Germany have done successful commercial transformation of their natural resources. These countries earn huge foreign exchange from herbal trade. India is the poorest performer in this sector, despite having numerous inherent strengths like rich bio-diversity, popular TSMs, greater cultural acceptability and trained man power. It is high time we must analyse, in retrospect where we have erred?

Global Herbal Market – A Bird’s Eye View

The statistics of the market reflects its good health and paradigm growth in the future. The current market value is estimated at around US $100 billions, which is growing at 7% p.a. and is expected to reach US$ 3 trillions by 2050. The overall improvement in economic condition of the world population and growing consciousness for health makes it imperative that health related expenditure will continue to grow. Considering the apathy towards synthetic medicines and better efficacy on part of herbals in preventive and promotive aspects, a bigger chunk of health expenditure will go into herbal sector. Thus brighter days are ahead for herbal industry.

India’s Strengths

India comes under one of the 12 mega bio-diversities in world.  It has a enviable flora of which 15000 plants have known medicinal uses.  It is an agriculture based country having varied geo-climatic conditions to facilitate growth of a wide range of plants. To supplement this India brags of many popular and vibrant TSMs like Ayurveda, Unani, Siddha which uses herbs as the primary tool for their therapeutics.  

Where India has Faltered?

India has a miniscule share in the global herbal market for its failure to transform the naturally gifted opportunities into economic boons. The stake holders in the Indian  Herbal Industry lack a clear and complete understanding of the entire gamut of activities of the industry. This piece meal approach deters Indian players to compete effectively in global scenario.  One needs to traverse the entire cycle of operations involved to flourish sustainably.

The Roadmap

The road for a herb seeking global placement commences from its selection and ends with strategic placement of its value added products in international market. The market looks for a herb with quality in a good quantity for a consistent period of time.

Selection of a herb

1.  Segment identification – to which therapeutic segment
the herb caters like adaptogen, aphrodisiac, etc

2.  Market value of the segment

3.  Supply viability – Collection / Cultivation

 

Cultivation

To have a continuous supply of consistent quality material the age old of practice of collection from the wild would not suffice because both quantity and quality will be unpredictable. So the industry has to resort to cultivation. The following approach is needed in medicinal plant cultivation to produce international quality material.

Suitable variety selection w.r.t yield and quality
POP as per GAP (Good Agricultural Practices)
Suitable Post Harvest Management to retain the efficacy
Grading, Storing and proper packaging  
Quality control by
       Physico-chemical constants
       Limit tests for Pesticides, Micro-organisms, Heavy metals
       Product development

Research & Development

This is the grey area in herbal market. The claims that herbals make often is not backed by significant scientific basis to be accepted by the users. So in the long run they are perished. To avoid this R & D has to be fortified.

Literary Research
             Exhaustive Data Bank
             Hypothetical leads

Plant Research
             Hardening & acclimatization of species
             Propagation of superior species by Micro-propagation, cloning

Phytochemical Research
            
Isolation
            
Characterization
            
Extraction
             Standardization
             Pharmacological Research
             Safety study
             Efficacy study
             Dose fixation
             Pharmacokinetic findings

Clinical Research
            Phase – I

            Phase – II

            Multicentred, randomized, double blind, placebo controlled, cross over study 
            pattern

Processing & Extraction

With changing times user friendliness is also become very important and crucial attribute of a herb. So the traditional dosage form has to give way to modern forms. By extraction the volume of the dose goes down, the potency of the herb is increased and a standard product can be given. Processing and extraction has to follow this pathway

Appropriate technology to enhance therapeutic principles

Optimum extraction conditions

Standardized extracts

Formulation

The end user needs an array of choices making it imperative to develop as many formulations possible from a herb by

Segment identification

Hypothetical leads

Lab scale manufacturing

Safety & efficacy study

Good Laboratory Practices (GLP)

Products

Several products ahs to be in the shelf to sustain the interest in the herb. The products should be manufactured

as per cGMP

Validated by Pre- Clinical & Clinical trial

Shelf life study

Packaging & Labeling

 

Marketing

All these activities is half of the job and marketing is the other half. The market placement calls for meticulous assessment of the pros and cons to render the venture successful.

Potential market identification

Current trend & Future projection

Approval from authorities

Market promotion

Conclusion

By traveling in this path a herb can be successfully placed in the global market to stay and rule. India has many potential herbs which if properly groomed can make it the global leader in this sector and can be a very handy help in uplifting the country’s income.

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To know more about Global Herbal Market, mail to info@hitayu.com
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Debate of the issue

MEDICINAL PLANT FARMING & ITS EFFECT ON THERAPEUTIC PRINCIPLES OF THE PLANT

With growing demand of medicinal plant produce cultivation has become the only answer to meet this demand. A lot of farming activities has been going on for selected medicinal plants. owing to the commercial profitability agriculturization of medicinal plants has by and large overlooked the geo-climatic requirements of the plant, if the yield is satisfactory. But therapeutic principles of the plant depends upon its metabolic activities which is significantly influenced by the geo-climatic inputs. A neo-school of thought advocates the plant should be grown in its native to get the maximum therapeutic benefits. Scientific advancements like genetically improved varieties has also made the scene more complicated.

We at Hitayu, feel this is a very crucial issue affecting all the stake holders of the industry because we should what we are producing and if they mitigate the supposed expectations. Thus Hitayu  team ahs chosen this as the debate of the issue. We invite your opinion on this topic so that we can compile these opinions and a solution in the form of the essence of these interactions can be derived.

Expecting your kind co-operation. Please mail your opinion to info@hitayu.com

 

Herb of the Issue – Aloe vera

Dr.Purvi Shanghvi

Technical Director

Hitayu

info@hitayu.com

Aloe vera is a therapeutically versatile and highly popular herb since the dawn of human civilization. The popularity of aloe stands unabated till todate as people all over the world is still using aloe's unparallel healing power to their benefits. Aloe has multifaceted uses like health care, personal care and cosmetics. It can be used in various forms like raw , gel, juice, powder, etc. and can be used both externally and internally.

The Classical Aloe  
Aloe vera was known to Indians for its medicinal values since time immemorial in the name of Ghrit Kumaree. It has documented evidence of being medicinally used in Vedas, Ayurvedic classics like Charaka Samhita, Sushruta Samhita, etc. as a laxative, as a liver tonic, as an wound healing agent, as an adaptogen, etc. It is grouped under Rasayana group of herbs which qualifies it to be consumed regularly without any apprehension of side effects. Ayurvedic physicians use freshly cut leaves or the dried leaf juice of this herb, popularly known as Musavvar.

 

Botanical information
Several species of the genus aloe has been in use under the common name of aloe viz. Aloe vera, Aloe barbadensis, Aloe ferox, Aloe chinensis, Aloe indica, Aloe peyrii, etc. Amongst these Aloe vera Linn syn. Aloe barbadensis Miller is accepted unanimously as the correct botanical source of aloe. In most reference books Aloe barbadensis Miller is regarded as the correct name but as per the WHO monograph Aloe vera (L) Burm f. is accepted as the legitimate name for this species. The genus aloe is placed taxonomically in Aloeaceae family.

Aloe vera is a succulent, almost sessile perennial herb growing upto 1 meter. The leaves are radially arranged in two or three circles. Each leaf is 30-50 cms long and 10 cms broad at the base having an indented margin. The leaves are pea-green coloured with occurrence of white spots when young. Bright yellow tubular flowers appear in a spike.

Aloe ferox is an arborescent perennial shrub. It has a two to three meter long stem crowned by a large rossette of numerous leaves which are glaucous, oval-lanceolate, 40-60 cms long, thorny on the ridge and the edges. Red, yellow or orange coloured flowers occur in a raceme.

Distribution
Native to southern and eastern Africa, and subsequently introduced into northern Africa, the Arabian peninsula, China, Gibraltar, the Mediterranean countries and the West Indies . It is commercially cultivated in Aruba, Bonaire, Haiti, India, South Africa, the United States of America, and Venezuela.

Plant materials of value

1.  Dried Juice
This is commercially known as aloe or musavvar. This is the solidfied juice coming spontaneously when the leaf is cut out of the cells in pericycle and adjacent leaf parenchyma. This juice is then dried with or without heat to give a strongly bitter substance having a characteristic disagreeable odour. This is known as aloe in the market. Three types of aloe are available in market depending upon the source plant viz.
 

  • Curacao aloe : a dark brown coloured substance sourced from Aloe vera
  • Cape aloe : greenish brown coloured aloe sourced from Aloe ferox
  • Socotrine aloe : reddish black coloured aloe sourced from Aloe perryi baker.


2.   Aloe Gel
The clourless mucilagenous gel obtained from the parenchymatous cells in the fresh leaves of aloe vera. It is slightly bitter and odourless. The gel loses its transparency if extracted after 3 hours of plucking the leaves. Commercially available aloe gel is stabilized for maintenance of its potency.

3.   Aloe Juice
A colourless, transparent water like juice obtained from fresh aloe leaves. It is tasteless and odourless.

 

4.   Spray dried powder

A pale white coloured, bitter powder obtained after spray drying the gel.

 


The international demand for aloe is mainly evolves around the gel and juice which should be anthracin free because anthracin is

1.      bitter in taste

2.      facilitates discolouration of the gel
 


Phytochemical composition


1.    Aloe : Hydroxyanthrone derivatives mainly Aloin is found in 15-40% concentration.
2.    Gel and Juice : Carbohydrates(0.3%), Water(98.5%) and polysaccharides.

Uses

1.   Aloe

  • Constipation
  • Peptic ulcer
  • Tuberculosis
  • For reducing blood sugar
  • Skin diseases
     

2.    Gel and Juice

  • Wound healing
  • Anti-inflammatory
  • Burn treatment
  • Adaptogen
  • Cosmetic use
  • Dietary supplement

Current Market Scenario

Raw Material
The current global turnover of raw aloe leaves amounts up to US$ 70-90 million dollars, which is expected to grow at a rate of 35% in the next five years.

Processed Derivatives
The current global trade is estimated at around US$ 1 billions and is steadily increasing.

Value Added Products
The world market for aloe based finished products is stated as around US$ 25 billions.


Present Global Players

USA supplies the major bulk of aloe in world market having a share of 60-65%, whereas Latin American countries supplies 20-25% and Australia, China and India combinedly has a market share of only 10%.Keeping this high rising global demand and India's conducive geo-climatic conditions for cultivation of Aloe vera in view, cultivation of this herb must be promoted. This will fetch India good foreign reserves as well as domestic economic prosperity.

Cultivation practices

Propagation Method -  
Pups (root suckers). 

Plantation method - Ridges 

Planting Material Requirement Per Acre -   5500. 

Soil requirements  -  Loamy 

Climatic Requirements   -  Tropical, Sub- tropical 

Area Where Cultivated -   Through out India up to 5000ft above mean sea level. 

Spacing          - Plant to plant - 30-45cm
                       - Row to row - 60cm 

Typical No. of Plants / Acre   - 5000. 

Sowing Period    -     June - July (monsoon) 

Harvesting Period  -  After 12months. 

Manures & Fertilizers  - FYM ( 5-10 Tons / Acre ) 

Irrigation -   Rainfed, Sprinklers.

Useful Part -   Leaves. 

Harvesting -   Manual cuttings after 18 months and 3 – 4 harvests can be d. Gel extraction (with in 3hrs of plucking).  

Yield Per Acre -   525 qtls/ha

Economics -    For production in 1 acre of land it cost nearly Rs.50,000.00 while the profit comes around Rs.40,000 per acre. 


Processing unit

Aloe to be transformed into marketable form needs processing. The unit should preferably be located nearer to the cultivation site. The processing unit with a capacity of 1 ton gel output per day costs Rs. 20 lacs. The extraction of aloe is a labour intensive work so the quantity that can be processed also depends upon the availability of labour. 

Aloe vera is a versatile economic herb and progressive farmers can go for the plantation of it. Buy back arrangement from both Indian and foreign companies along with processing technology is also available. Cultivation of this herb in a large scale can make India move towards the leadership in Global herbal market.

 

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To know more about Aloe vera, mail to info@hitayu.com
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© Reserved with Chief Editor, The Samjalpa, HITAYU 2003